A bit more #ldlcholesterol and #apolipoproteinb or #apob100 as well as #triglycerides and #chylomicrons before we look at lipid panels #atherosclerosis #histologyin3d

let's take a look inside LDL. You met cholesterol in our last video and if for where alone floating in the blood it wouldn't mix with blood since blood is 51% water. This reminds me of something else that's in the blood, another lipid that we haven't met yet. This is a triglyceride also found in the lipid panel. So we have cholesterol, we have triglycerides, two lipids that would not mix with blood since blood is made up of a lot of water. So both of these guys need carriers and these carriers are called lipoproteins. Lipoproteins meaning it's a mix of lipid and protein. LDL or low density lipoprotein is one type. We start with one layer of phospholipids. Yes, phospholipid. So lipid here and then we can tuck cholesterol into this layer as well. Remember it's a structural lipid and since this is LDL we're going to add lots of cholesterol in here and a bit of triglycerides. If you've heard of chylomicrons or chylomicron remnants there's more triglycerides than cholesterol in those. And now we close it up and I know I've been saying lipid, lipid, lipid, lipid. Whereas the protein, the protein's on the outside here. For LDL it's apolipoprotein B100 or apob for short. Apob 100 level checks. This is a blood test that would measure the amount of protein you have which could check your risk for cardiovascular disease. High level would indicate a higher risk.