Diabetes tipo 2 #diabetes #harrypotter #snape #fisiopatologia #pagina394

[music] Today we'll talk about the Melitos type 2 diabetes. They go to the page 394 of Cerebro Medical. To begin with, they must understand something fundamental. So that many cells can capture glucose, especially the muscles and the device. They need the action of a hormone. The insulin. I think that's something basic that even you should understand. As I suppose you all should know, they are produced in the beta cells of the pancreas. That, frankly, should already dominate it. But I'll remind you. The insulin is a specific receptor in the cell surface. This is an active union of a series of signals intracellular that allow the glute-4 transporters to move towards the cell membrane. Without this mechanism, the glucose does not immediately enter the cells and begins to accumulate in blood. And there is precisely the problem. In the diabetes, Melitos type 2 can occur one of two things or even both at the same time. The insulin resistance or the progressive deficit in insulin production. There is a clear relationship between obesity and insulin resistance. The easiest way for them to understand it is to imagine that the excess of fat interferes or, let's say, blocks it with the correct action of insulin. So the pancreas try to compensate. Does anyone know how it does it? No? What a disappointment. It's obvious that producing more insulin. That's why, as I hope they can deduce, many patients, before being diabetes, present hyperinsulinemia. That is, they have elevated levels of insulin, with the passage of time. The beta pancreas cells begin to get agitated. The pancreas can't produce enough insulin to compensate the resistance. And when that happens, the hyperglucemia appears. The ligado also contributes to this metabolic disaster. In normal conditions, the insulin indicates the ligado that decreases the glucose production. But when the ligado returns to that signal, it continues producing and releasing glucose to the blood. In addition, it also produces more acidity. As you can see, the drags are fed up with itself. More fat produces more inflammation and more insulin resistance. More insulin resistance demands more work from the pancreas. More pancreatic work leads to the lack of beta cells. And when beta cells fail, there is less insulin effective. An elegant cycle in its cruelty. I am convinced that its weakens have not understood everything that will have to go to www.cerebromedicopunto.com and read the page 394.